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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ca849b6640cfd9ae8c035d454aadbbf285b834bd992d6caad75680a3008a293' 
  AND token = 'E80S8GQcTcZh/seF+swGU32Y4M06UtgNciUcad52B+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}