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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b67e9f155e4721f72007377e51347a7f9fdf7c6d776629fc19c81321b7a1ae4b' 
  AND token = 'C6Qp7h1HqiZrZrPW5nzYy6xXScFgpcf4+wF45yeuwJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}