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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f6e2019d9b5f2c13694de3ec522e369462fc13329e9b576ca7dd2ed33575a18' 
  AND token = 'usPtBPYpM4Jchn9lk7fVQs6R3IvlOp2rf6WjJtu9h3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}