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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '712e855a81cadaf71f254d4942d1c9c02c7159c28de41ca747bc56d4c4fd3b79' 
  AND token = 'gWkoBeM98TiEks+gbln8cYqA/7iH7j9NBrZ5ZGLHCJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}