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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '644de982b0b7acc48789531aa7cb270bdde539a749317dbb2d1c3e046733b808' 
  AND token = '2S786CVaDOTo2QxNSYWLZvmkZIXn682ue8FDJre4ORI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}