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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd818b553460a7f43a4d2b46dfe048d8b9f7a84a921bf039da5a9e5ab64d4fdd3' 
  AND token = '5zd3nxM3vtSoX3ILN5aWxAzmrzo+Vkw/rhYuZ61bI5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}