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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d818b39aa21fb5e798001ad2704d4bd2bd4343c127f0218a3a20769aef69c31' 
  AND token = 'qmpI/rIhB6d6UXPJur6TEFXgH5MAa0l6T4jI4vwxkUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}