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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a6f080cff955fad4d8d174e16b35f3904f100369d50f3055004f93a0279b3b5' 
  AND token = 'lM+13krrGzLZdD7xSRKOa8st+avUA+FTtNTmqnwpvPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}