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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8f8a53ea7f2ecffd7d4df4f39273feb9bed29b5816e51677efdaaa8233de091' 
  AND token = 'RsFHzEkGvHchzwPoRMuyS7Nfeua5RI9bUuzUJkUz3Wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}