SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42c076339ecf150d5e9163ef88d6a27d57bfce8981f076f1c3595da1107aac41' 
  AND token = 'IT6ClyDoBWI2WIdb56c7tJ6ZQ/JBLty5YV+EUAtbH7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}