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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10c45668869976946f6f348bb86739918cde48db91d58cb8f410146b2a8a39f3' 
  AND token = '/Rcal2ro69X99itVdBQB5pLzBZXcW+8ZelVEXceH+eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}