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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e53eac18ef710a1d78d55ac7c28e63ba5adee9b5353f95806f5b85fb11ed11da' 
  AND token = 'mOMgnSTTK9rt7Pjgk92w1So3R0sVKg1ZAd4D6xsdnGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}