SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b9cdf25eca8b33baea06616048ee417193af5fdc7751fe73c770615f64edc0' 
  AND token = 'mORkbZBHFUtUJfW+9ioYrCc7WwkltGbgm6v454dXCcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}