SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62fa99e2bd85b9e137cc4df7dff74d13f3c525a7c0886f17a7c40548771c6b35' 
  AND token = 'yOAiZm6Vi+VDSLoOW3uD6rmP+HY+KM3+eES+q3thLBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}