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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67a626778f050a526a7e36a33d567181c598bbb3435ba055e244e76c6796d5b9' 
  AND token = '9+6s1x5pTMoSAoGXOllhExl574DHaTTJUK7GRqHPgdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}