SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '377a80f400c8e5d9785ff4016d9a18411feeb87815e44eac7175ff40d9a16a35' 
  AND token = 'YmADWRLuPVefKNIn8Sebdu2Opou4iHT8Ok2Zc0vkx58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}