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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdaaec09096b0479d244be81f9b948360b9e2984a6e80473d978bbaea98f01ba' 
  AND token = 'GJlRseDg2VsOddSnN9eFQKo7XM8MP3QeO1UHvW8dgGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}