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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82a67c7a2100dc4223e3d2b5fa2bab64ee989e7f943c48f98aee1c09497f1c33' 
  AND token = 'zfsDxJk/4HY+JZZvzhbIdzugbDQDJhhuDiNsNEbkBJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}