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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61172bc02b1c7a49040d96f66e7b7ac9003ba45993a62fda050ca195be4f4354' 
  AND token = 'LMJQ/btzE/p0oD+4OyvNPKm3hoMEetEqKaZwt1DMyQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}