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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18dd4bd37a1d75beff4e1313e84ed9d62036d6e00f9fa3f564e7e0ff21670e70' 
  AND token = 'NgI6nmQtz4RKOuXhzIBJOv50K77h1wru9/F+cELOA4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}