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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36f21eb8a733b22fd64e8b0b102d43a6b8beb046e3c5a3f6c3e4c74e4eb86271' 
  AND token = '1ukZ8XQu5VQvr1/nlJrIgVHmVoXMMbse+Us0T+85pEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}