SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '811c774fb76f05013d4a6465109d3cb4b0526eddb702a86d31422da83c71334d' 
  AND token = 't4Umj3oLv4jzZJRZMYsPQ+QGp5yxUkddCGCrg3nQxAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}