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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '563b7ad63f3786fe9e5707e6b839f37dd2ffeb939b49ced8c34e2a40fa3d6635' 
  AND token = 'dWT7F/eqDox188aRjudPOxuiHu5Gp/DlqYxCwYDr3qA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}