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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48610a37f6a2e5bb475c5e034815e75c206706cbe8b55a50c96edc7a64e7d9b4' 
  AND token = 'i59fiZudv30vviA9krJ8R6ZkOdgmNX2o2jjh3w0hQ3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}