SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad7390230f9c6080a3f40b4e5554c4b216564018ba2ff962d97c42ccdbce5276' 
  AND token = 'yUqb4jynsvawVpRD+kEucmzHM61L+Y+1N4/z0NQNYk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}