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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04f46e37caed292ce355f931f80428963908923ad5cc9a70cf8461bc78c12f10' 
  AND token = 'r71akVZ8rbeL50WY0npAgwhOP2DvA0aZyO5Rpy9KOfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}