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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac12eb4abda37e8ceeecfd1c10a843461c9130411f4a03819b091044e6914255' 
  AND token = 'QcBWLFaTGDMiz6nNKKUvPJvDveVkQ6u29CkUsNi1CgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}