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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '182ad7744d914ce6ecf3786bbf6f8bd2fda4d8b919e0c0fcac433e54edd56d29' 
  AND token = 'c6IQRb89U+GbpkHFYWC55WPBo79PF5ba9u3il5dEU88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}