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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2972720dd207bc000538c582544a85297ae2ad4ca06f57e8b6ea47c82db34c2f' 
  AND token = 'knCU/T8maz+LxQG3bb8I/FYpPOZM3Qn5fuFi7Vb1eY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}