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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85e179f3c278c562029f0b87b693fb65ebcf2d38ce12ee9e4486159ce093a3c5' 
  AND token = 'zrf3+lXkIWwD8gUH2+NX3icFtSmyh5qjQc+4FJpEGFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}