SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ab9822e80fe24f799121c33d7c3b89e6bbe2b581d296577d6339165984a7255' 
  AND token = 'j53/HpcldYmhk1EgzhjSytQrJC3Qk5TiCDDhrikeMY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}