SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5738b59a4f457c73d862b16c004186f6dc492ad4a2b0dcbeadc673fb36c3ac1b' 
  AND token = 'MO8lxv03n41HdA9y0bqM5/2mRMhp3JjWLXE+x5hq1Ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}