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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90be5ed22d154ade005449e54575426756aadbd22a59cf353a8beedc8323e67e' 
  AND token = '9z75/+Xy1sWQaoUZMciWnDoYURlF4p0huv6SpBQ/5yw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}