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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5143a7d653e2f027de0f0eafbf6627c17f29e85c148a35f7026a2f3502445e8e' 
  AND token = 'X+jegidpXwYtxcq3XyrHegxlKLJx3LpGqLXqsx3oj84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}