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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '96faa0035e50a108f267e882dba07299abd8b0e675d27e7b752b236d0bf7206d' 
  AND token = 'ic16QvRFBQBt3TawkfOGT7Bx2qx+uzFX2suYtaO2Yvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}