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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '510b2d1088cbe7c7525cf63379b6ed0e2ee05890afed8491c9de45f6f30c6f80' 
  AND token = '2f0NmK4qtjc4pyYXTQ92ogjjpzCViTLfT3aiAqWfgzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}