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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41aa375c16ec9766d20c5c251bdf6ff1a48b3b2727633dac7604d72a8580cdc8' 
  AND token = 'edwtvknY91Kcus1D/ip9bsrTXSSFRBjgWY5ej4iFhSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}