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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dae8ef1d9df93bde38729a2da2f594a364bb5f331a925acba28eb3408b3d5ef8' 
  AND token = '43MI4AJ8Y2bFGk7Z8UeDkxDg+cKfRk/PhqNon5kATo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}