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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2147fe2f2b95267cdd2ecd45fb45238ccb7c87ea9fd2b443a31affacdc55491a' 
  AND token = 'mqNv2viFen/qsHb85vQL5J612WEns20TbyOl28rrvQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}