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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2408a53c9c68ed9f14d6c4532a7bc02ebbdb9d13239a62729f90138263ff1294' 
  AND token = 'sOr/AOlEslH1kJq+HnowgwFwlF8ItYlWk/Ju+Kae/l0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}