SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c06cda64113bd4fa0774951dcba8a457fd79d87abab9c3606575297fb2257ac9' 
  AND token = 'mShC1nq0RkWIn+iPUBXJGG1LEvS1FWii31VFRIhG2Y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}