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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '016c8a33f57307abfcf7dccf0c16b8373313f821d5be51dfb6a0065dcea3b51c' 
  AND token = 'GdRirzfY19yhw7qeYrDK7y1OOHZteESb7uPXiVLs5oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}