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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d6de1059d9feb52708a956950e68a02aa6ac5c84eb4848640065f317d52bd8a' 
  AND token = '1IXt+g/c+Umg+Go3XKSyBKKEcBrqNTIBe0qgIEvSSE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}