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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3b157ad4b0633fe2b2e7893a546a77b8ffe26757e7537deb7a221ceb13324e1' 
  AND token = 'Gl3giwjwQf/DOPjc5YYwMUEHQZXao+G1la4u4gSQ0WM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}