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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9662309becf08b9b485541e38fc68bed4df66f2bd514897f788c1479466826c1' 
  AND token = 'hF4SdXwYmmrtrjbHwjh613VISBTWM0A+kLEc69fPTkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}