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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '349a33e5a4ededcfc47755f44e185f7850e2747b46e12fdea9d463088a8bdeff' 
  AND token = 'joxHaQvKEpbLfQwPiVGUzf3tVkInn47fK1o4VsRyMpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}