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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77f76f57ba62f17a0ba16463e247939a899b04d5527ae9fa4c417ee16d1eb443' 
  AND token = 'tbdo8kTX7VS3C6x2qeHJvaaBUyesE+Af8pvhqa3FWJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}