SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c3309ccde0fc64e9e2606824156ab830c1e063307936a2aed4b43f49c80e0ab' 
  AND token = 'r2UuPMMzZfo3yKnsqocJfzfu8m2gEhLTBaC3iV28hdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}