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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6473f5a6ff8558706146041e635b1be5ca98a02a61b4f38ba2491aa744aecbb6' 
  AND token = 'EjlIPd040PX0z48rhsduHh90QKOykK8gvlhFi9F+WjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}