SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f25589f00d190938aa9dc67d513d4c9cb011002cc54aefb7d41b1349db288cf' 
  AND token = 'yqnGVOFjvYAqpTOUTgJvWzrAhGB76e0BhaUOHHnVCg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}